Molecular Mechanisms of Coronary Spasm
نویسندگان
چکیده
منابع مشابه
Editorial Comment Pathogenetic Mechanisms Coronary Artery Spasm*
Coronary artery spasm was first proposed as a cause of spontaneous, recurring angina1 attacks over a century ago (1). Because this brilliant clinical intuition could not be demonstrated at postmortem study, it fell into progressive disrepute until, in the early 1950s coronary artery spasm was considered “the resort of the diagnostically destitute” (2). In 1959, the notion of coronary artery spa...
متن کاملContemporary Reviews in Cardiovascular Medicine Mechanisms of Coronary Artery Spasm
The term coronary artery spasm (CAS) refers to a sudden, intense vasoconstriction of an epicardial coronary artery that causes vessel occlusion or near occlusion. Although CAS may be involved in other coronary syndromes, it represents the usual cause of variant angina. The variant form of angina was first described in 1959 by Prinzmetal et al,1 who used this term to indicate that angina attacks...
متن کاملCoronary Circulation After Coronary Spasm
To examine whether acute myocardial ischemia activates the coagulation system and platelet activation in the coronary circulation, we measured plasma levels of fibrinopeptide A and j3-thromboglobulin in the coronary sinus and the aortic root simultaneously in 15 patients with coronary spastic angina before and after the left coronary spasm induced by intracoronary injection of acetylcholine and...
متن کاملMultivessel coronary artery spasm.
A 60-year-old patient with variant angina was shown to have myocardial ischemia in two different regions supplied by separate major coronary arteries. Neither artery had significant coronary atherosclerotic obstruction. Ventricular fibrillation was noted during ST-segment elevation in anteroseptal leads. The attacks of pain and arrhythmias disappeared during nifedipine therapy.
متن کاملCoronary Artery Spasm
Case presentation: A 37-year-old man was admitted in the early morning hours to the emergency department after experiencing excruciating chest pain. The patient was a heavy smoker who gave a history of several previous similar but less intense episodes of pain during the past 2 years; most of them also during the early morning hours. One of his earlier attacks was associated with sensing his he...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1995
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)46269-0